A Bioinformatics Tool to Identify Nested Motifs
نویسندگان
چکیده
منابع مشابه
identify regulatory motifs.. Bioinformatics. Vol 19:18 (2369-2380)
Identification of regulatory motifs in DNA sequences is made difficult primarily by their degeneracy. Computational techniques to find statistically over-represented sequence profiles are aided by inputting sequences in which motifs are fairly certain to be found. Prudent selection of orthologous genes ensures that species are sufficiently diverged to have low sequence similarities in regions n...
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UNLABELLED We describe MotifScorer, a program for systematic genome-wide identification of transcription sites. The program uses a compendium of gene expression microarrays and implements state-of-art partial least squares (PLSs) based regression and stepwise regression procedures. Candidate motifs from the upstream sequences of groups of co-regulated genes are identified and assigned a score u...
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ژورنال
عنوان ژورنال: Journal of Computer Science & Systems Biology
سال: 2017
ISSN: 0974-7230
DOI: 10.4172/jcsb.1000247